Biological Physics & Quantitative Biology
22 Research Groups
Biological Physics applies approaches and methods of physics to unravel the underlying organizational principles of biological systems. Quantitative Biology addresses problems in biology, biomedicine, and ecology through image analysis, theory, computer simulations, and data visualization. Dresden is an internationally recognized hub for scientists working at the interface between physics, biology and computational science. We focus on the investigation of phenomena across all relevant scales – from individual molecules to sub-cellular organization and cellular properties to tissues, organs, and organisms. We ask how complex system behavior on a large scale can emerge from simpler physical and chemical interactions at smaller scales. We address these questions through close collaborations between theoretical physicists who provide the conceptual and modelling framework, experimental groups who develop and apply state-of-the-art techniques to obtain quantitative data, and cell and developmental biologists who provide the necessary biological expertise. Our tools include image analysis and image quantification algorithms, model-based image segmentation and cell tracking algorithms, adaptive particle methods for spatio-temporal simulations, parallel high-performance computing, multi-scale mechanistic model simulations, and deep learning.
Image © Diez Group
Research Groups
Ellen Adams
TUD PoL, HZDR Physical Chemistry of Biomolecular Condensates
Sebastian Aland
HTW Dresden Modeling and Simulation of Dynamic Biological Interfaces
Elias Barriga
TUD PoL Biophysical Mechanisms of Morphogenesis
Currently Recruiting (call opens 20 February 2026)
Jan Brugués
TUD PoL Self-organization of living matter
Lutz Brusch
TUD ZIH Spatio-temporal pattern formation in cells and tissues
Otger Campàs
TUD PoL Physics of Embryonic Self-Organization and Morphogenesis
© TUD CMCB, Magdalena Gonciarz
Stefan Diez
TUD B CUBE, TUD PoL Molecular transport in cell biology and nanotechnology
Miki Ebisuya
TUD PoL Cross-species comparison and manipulation of the organoid zoo
Karim Fahmy
HZDR Structural basis of biological switches and biomolecular recognition
Elisabeth Fischer-Friedrich
TUD PoL Mechanics of active biomaterials
Benjamin Friedrich
TUD PoL Biological Algorithms: Spatio-temporal dynamics of cells and tissues
© Jan Greune
Felix Müller-Planitz
TUD MTZ Epigenetics and Chromatin: How chromatin forms and how it affects cellular functions
M. Teresa Pisabarro
TUD BIOTEC Computational approaches to functional genomics and rational engineering for target/drug discovery and biotechnology innovation
Anna Poetsch
TUD BIOTEC Biomedical Genomics
Shervin Safavi
TUD Medical Campus Computational Machinery of Cognition
Helmut Schießel
TUD PoL Theoretical Physics of Living Matter
© TUD CMCB, Magdalena Gonciarz
Michael Schlierf
TUD B CUBE, TUD PoL Conformational changes in biomolecules and enzymes
© BIOTEC
Michael Schroeder
TUD BIOTEC Computational Drug Repositioning with Networks, Structures, Text & Ontologies
Anna Taubenberger
TUD BIOTEC Oncomechanics
Xingbo Yang
TUD PoL Bioenergetics of Self-Organization
© B CUBE
Yixin Zhang
TUD B CUBE Drug design and screening: from biochemical methods to 3D model system